COLOGUARD® TEST: INSTRUCTIONS
How to use the Cologuard test
Noninvasive, simple, and effective, the Cologuard test detects 92% of colon cancer1. Learn how to use your Cologuard kit with our step-by-step guide.
Choose your desired language for the video below to see how easy Cologuard can be to use
- English (US)
- English (US)
- Español (Spanish)
- العربية (Arabic)
- Français (French)
- Kreyòl Ayisyen (Haitian Creole)
- हिंदी (Hindi)
- 한국어 (Korean)
- Português (Portuguese)
- Русский (Russian)
- Tagalog/Filipino
- 粵語 (Cantonese Chinese)
- Tiếng Việt (Vietnamese)
- 国语 (Mandarin Chinese)
How to use
Watch this video for an in-depth guide on how to use Cologuard in your language.
The Triple S method: Set up, sample, and ship
Three easy steps to get screened for colon cancer.

What’s inside your Cologuard box
- Return shipping box
- Sample container
- Probe + tube
- Bracket
- Patient guide instructions
- Sample labels
- Bottle of liquid preservative)
Pack it, send it, get results fast
We’ve made it easy to ship your sample back to our lab using a prepaid label. Once we receive your kit, your test results will be available within 2 weeks.

Frequently asked questions
Our lab needs a stool sample that looks like your usual bowel movement. For size reference, please look at the bottle of liquid preservative in your kit. Your stool sample should be bigger than the bottle’s cap, but not bigger than the bottle itself.
Not at all. Cologuard requires no prep, no time off — giving you no reason not to screen for colon cancer in the privacy of your home.
Our lab needs a sample that is typical of your stool. So if yours is normally loose, you can proceed with the test. If you are sick or have diarrhea, please wait for a few days until your bowel movement returns to normal.
Your stool sample should be mailed back within the same day or the next at the latest. A prepaid UPS label is already attached to your shipment box. All you have to do is peel off the first label that has your shipping address. You can then drop it off at your nearest UPS store or schedule a pickup.
Just call Customer Care at 1-844-870-8870. If needed, we can ship you a new Cologuard kit at no additional cost.
Just log in to your account to access your result, which will be available within two weeks from the time our lab receives your sample.