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FAQs

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ABOUT COLOGUARD® GETTING, USING, AND RETURNING A KIT RESULTS & INSURANCE ADDITIONAL QUESTIONS

About Cologuard®

  • What is Cologuard?
    Cologuard is an FDA-approved, non-invasive, at-home colon cancer screening test. It’s for people 45 or older at average risk for colon cancer. RX only. Learn more →
  • Why does screening matter?
    Colon cancer is the most preventable, yet least prevented cancer. But when caught in early stages (I & II), it’s treatable in about 90% of people.

    National Cancer Institute. SEER cancer stat facts: colorectal cancer. Accessed Nov. 23, 2022. https://seer.cancer.gov/statfacts/html/colorect.html

  • What does Cologuard screen for?
    The Cologuard test detects the DNA and blood released from altered cells, and can detect both precancer and cancer.
  • How does Cologuard work?
    Cologuard uses advanced stool technology to detect the DNA and blood cells released from abnormal cells, and can detect both precancer and cancer. Learn more →
  • How effective is Cologuard?
    Cologuard found 92% of all colon cancers (and 94% of all stage I & II cancers) in a clinical study of 10,000 participants ages 50-84 years old, of average risk for colorectal cancer. Learn more →

    Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-1297.

  • Can Cologuard detect polyps?
    Yes, Cologuard can detect some precancerous polyps that grow on the wall of the colon and may develop into cancer. Learn more →

    Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-1297.

  • Who is Cologuard for?
    Cologuard is for adults 45 years of age and older who is at average risk for colon cancer. Cologuard is not a replacement for colonoscopy in high-risk individuals.
  • Is Cologuard FDA-approved?
    You can request Cologuard through your healthcare provider. Requesting Cologuard through an online telehealth provider is also an option. Click here to get started →

Getting, using, and returning a Cologuard kit

  • How do I get a Cologuard?
    You can request Cologuard through your healthcare provider. Requesting Cologuard through an online telehealth provider is also an option. Click here to get started →
  • How do I use a Cologuard?
    Your Cologuard kit comes with easy-to-follow, step-by-step sample-collection instructions. You can also Download our Patient Guide or watch Helpful How-To Videos. Find help →
  • How do I return my Cologuard kit?
    Your Cologuard kit includes simple instructions for repacking, labeling, and postage (which we cover) to return your sample. You can also Download Return Instructions or watch a Helpful How-To Video. Find help →
  • I received my Cologuard kit a while ago and haven’t used it yet. How long is it good for?
    Your test order expires one year from the order date. Collect your sample as soon as possible, because timely screening is important to your health. We suggest setting a goal to collect your sample.

    Also, check the Cologuard box for the expiration date. If that date has passed, or you have other questions, call Customer Care at 1-844-870-8870. We can help you get a new Cologuard kit at no additional cost.
  • How will I know if my stool sample is “normal”?
    It’s important that your sample is consistent for you (loose stools are ok if that’s normal for you). However, if you are sick and have diarrhea, you should wait until you feel better to collect a sample. If you have any questions, call Customer Care at 1-844-870-8870.
  • I received my Cologuard kit, but I made a mistake collecting my sample. What should I do?
    We’re here to answer any questions you may have 24/7. Just call Customer Care at 1-844-870-8870. If needed, we can get you a new Cologuard kit at no additional cost.
  • I received a Cologuard kit but it is damaged or missing a part. What should I do?
    Call our Customer Care Center at 1-844-870-8870. We'll help you find out if you need a new Cologuard kit. If you do, we'll send you one at no additional cost.

Results & Insurance

  • When will I get my screening results?
    It typically takes under 2 weeks from the date you ship back your Cologuard kit to get your result. We’ll send them to your healthcare provider too so you can discuss your result with them.
  • What does a positive result mean?
    A positive result means the test detected altered DNA and/or blood that could be caused by a precancerous polyp or colon cancer. Talk to your healthcare provider about getting a colonoscopy, and any other next steps.
  • What does a negative result mean?
    A negative result means the test did not detect altered DNA and/or blood that could be caused by a precancerous polyp or colon cancer. We send your result to your provider regardless and recommend following up with them.
  • Is Cologuard covered by insurance?
    Cologuard is covered by Medicare, Medicaid, and most major insurers. Most insured patients pay $0.00*

    *Rate of coverage varies by state and region. Coverage rate only applies to Cologuard screening population.

  • How do I pay a Cologuard bill?
    Cologuard accepts payment either online or by mail. For assistance call our Customer Care Center at 1-844-870-8870.

Additional Questions

  • What are the CPT, HCPS, Tax ID, and NPI for Cologuard?
    Cologuard, Exact Sciences Laboratories NPI (145 E Badger Rd, Madison, WI): 1629407069 These codes are what your healthcare provider uses to describe the reasons they are prescribing Cologuard for you. If your provider has any questions, we can help. Contact our Customer Care Center at 1-844-870-8870.

    Cologuard is only billed under CPT code 81528. This code was established by the American Medical Association CPT Editorial Panel (and recognized by Medicare) with an effective date of 1/1/2016. It is also known as a HCPCS Level I or CPT Category I code.

    Cologuard, Exact Sciences Laboratories NPI (145 E Badger Rd, Madison, WI): 1629407069
  • Is Cologuard available in all US states?
    Cologuard is available in all US states. If you have more specific questions, please contact us at 1-844-870-8870.
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