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Cologuard® order for you

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Exact Sciences Laboratories is committed to helping people access Cologuard with telemedicine providers such as PWNHealth.

Links to all outside sites do not imply a recommendation of a particular provider by Exact Sciences, nor an endorsement of Cologuard by a telemedicine provider. Exact Sciences accepts no responsibility or liability for the content or services of other websites. All prescription decisions are made by the healthcare provider, based on the patient’s needs.

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What are my next steps:

  1. We will ship your Cologuard kit soon unless we need more information. If we do, Exact Sciences Laboratories will contact you.
  2. Your kit will arrive in 3-7 days.
  3. Once your kit is delivered, put it in your bathroom so it is ready when you are.
  • Why screen for colorectal cancer (CRC)?

    Why screen for colorectal cancer?

    Routine and on-time screening can make a big difference 

  • What is Cologuard?

  • What’s inside the kit?

    Shipping Box

    Shipping box

    Liquid Preservative

    Liquid preservative

    Sample Container

    Sample container





    Patient Guide

    Patient guide

    How to return your kit

    How to return your kit

    Sample Labels

    Sample labels

  • How to use Cologuard

    • Once you receive your kit, unpack it and review the enclosed Patient Guide.
    • Once you are ready to collect your stool sample, place the sample container into the toilet bracket.
    • Use your Cologuard kit to collect your stool sample.
    • Using the probe inside the tube, scrape your stool sample and then close the tube securely. Then. Fill the sample container with preservative. Don’t worry, you won’t have to physically handle your stool sample. Also, be sure to fill out both labels.
    • Plan to collect your sample when you can get it back to UPS® that same day or the next day.
      • Add a reminder to your calendar or phone on the day you will collect your sample.
      • Choose the no-cost return option that works best for you:
        • Drop it off at a UPS location – to find the nearest one, visit our location locator. Remember, some places are closed on Sundays or holidays.
        • Schedule a contact-free UPS pick-up. Call us at 1-844-870-8870 for help or self-schedule online.

For more videos on sample collection, check out our playlist.

  • Insurance

  • Negative Result
  • Positive Result
  • Negative Results

    What does a negative result mean?

    If you received this result:

    • Cologuard did not detect altered DNA and/or blood in your stool
    • You're unlikely to have colorectal cancer

    False negatives can occur. When you discuss your result with a healthcare provider, ask when you should screen again.

    Watch this video to better understand a negative result

    The American Cancer Society recommends that patients get screened for colorectal cancer again three years after a negative Cologuard result.1
  • Positive Results

    What does a positive result mean?

    If you received this result:

    • Cologuard detected altered DNA and/or blood in your stool
    • This could be due to precancerous growths, colorectal cancer, or some other reason
    • It’s important to know that this is not the same as a cancer diagnosis

    False positives can occur. When you discuss your result with a healthcare provider, you will need to plan a follow-up colonoscopy to confirm your result.

    Watch this video to better understand a positive result


1. National Cancer Institute. SEER cancer stat facts: colorectal cancer. https://seer.cancer. gov/statfacts/html/colorect.html. Accessed July 16, 2021.

2.Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70(1):7-30.

3. Patel SG, Ahnen DJ. Familial colon cancer syndromes: an update of a rapidly evolving field. Curr Gastroenterol Rep. 2012;14(5):428-438.

4. Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-1297.

5. American Cancer Society Guideline for Colorectal Cancer Screening. https://www.cancer.org/cancer/colon-rectal-cancer/detection-diagnosis-staging/acs-recommendations.html. Accessed July 23, 2021.

* Exact Sciences estimate based on historical patient billing from October 1, 2019 - January 31, 2020. Rate of coverage varies by state and region. Exceptions for coverage may apply; only your insurer can confirm how Cologuard would be covered for you.

Indications and Important Risk Information

Cologuard is intended to screen adults 45 years of age and older who are at average risk for colorectal cancer by detecting certain DNA markers and blood in the stool. Do not use if you have had adenomas, have inflammatory bowel disease and certain hereditary syndromes, or a personal or family history of colorectal cancer. Cologuard is not a replacement for colonoscopy in high risk patients. Cologuard performance in adults ages 45-49 is estimated based on a large clinical study of patients 50 and older. Cologuard performance in repeat testing has not been evaluated.

The Cologuard test result should be interpreted with caution. A positive test result does not confirm the presence of cancer. Patients with a positive test result should be referred for diagnostic colonoscopy. A negative test result does not confirm the absence of cancer. Patients with a negative test result should discuss with their doctor when they need to be tested again. False positives and false negative results can occur. In a clinical study, 13% of people without cancer received a positive result (false positive) and 8% of people with cancer received a negative result (false negative). Rx only. 

Request Cologuard online.
No appointment needed.