Free Cologuard Plus® return

Skip the drive, not the deadline.

Return your Cologuard Plus® test without leaving home with a free UPS® pickup.
Exact Sciences Corporation | October 2026
Cologuard Plus collection kit placed on a front doorstep.

Key takeaways

  • You don’t need to visit a UPS Store® to return your completed Cologuard® Plus kit.
  • Cologuard® offers a free UPS pickup option, allowing you to return your kit from home.
  • Pickup is a convenient solution for people with limited transportation, mobility challenges, or no nearby drop-off location.
  • Choosing pickup doesn’t mean sacrificing speed, especially when you schedule it promptly and select the earliest available pickup window.
  • A few simple steps can help ensure your sample reaches the lab on time.

Reliable logistics. Better care.

UPS helps move some of healthcare’s most important shipments, from pharmaceuticals and medical devices to lab samples and diagnostic tests. For organizations like Abbott, UPS manages the delivery and return of at-home colon cancer screening tests, helping make screening more convenient while ensuring samples get to the lab safely and on time.

When you're ready to return your Cologuard Plus® kit, getting to a UPS Store isn't always as simple as it sounds. For some, the nearest UPS location may be too far away, especially in rural communities. Others may not drive, have mobility limitations, or simply don't have time to fit another errand into their day. It will join the pile of things you’ll definitely handle right away. Probably. If any of that sounds familiar, you're not alone.

Many people assume dropping off their completed kit is the only way to return it. That can mean finding the nearest UPS Store, checking hours, making the drive, and waiting in line with a package you’d probably rather not discuss with strangers. The good news? You don’t have to make the trip at all.

There’s another way.

Cologuard offers free UPS pickup. Schedule it and the driver collects your kit right from your address, at no extra cost. Just go to Cologuard.com/returning-your-kit and click “Schedule a pickup.” If you can request online, contact Customer Care or call UPS general support at 1-800-742-5877. And just so we’re all on the same page, pickup isn’t the slower choice. Schedule it as soon as your kit is sealed, pick the earliest window offered, and your sample is on its way to the lab just as fast.

Schedule a pickup

Tips to avoid pickup delays

A few simple steps can help keep everything on schedule:

  • Keep your pickup confirmation and tracking information handy.
  • Keep the kit visible, but in a sheltered spot (e.g. front door, side door, covered porch).
  • If the pickup is missed or you need to reschedule, visit Cologuard.com/cancel-ups-pickup or contact Customer Care.
  • Plan on shipping the kit on the same day or the next day and avoid weekends and holidays.
  • Anyone without a permanent address or who live in Puerto Rico/ a U.S territory, call Customer Care to discuss a pickup plan.

By planning ahead, you (or your local UPS driver!) can return your test confidently.

Safe.
Noninvasive.
FDA-approved.