YOUR DOCTOR IS YOUR ALLY

How to talk to your doctor about colon cancer screening

From what questions to ask to seeing if a noninvasive, use-at-home test like Cologuard Plus® is right for you, we’ve made starting the conversation easier than ever.
Exact Sciences Corporation | July 2026
Doctor talking to patient about colon cancer screening.

If you’ve been putting off the “colon cancer screening talk” with your doctor because you aren’t sure what to ask or to expect, you aren’t alone. Feeling anxious, embarrassed, or fearful of its outcome is normal and common. However, it shouldn’t be a barrier to getting tested. Doctors discuss these screenings every day, so they’ve heard every concern and answered every awkward question you can imagine.

If you’re approaching 45 or have noticed changes in your body, an honest chat with your care provider is the best way to advocate for your health, and get the answers you need to make informed decisions.

Watch: It’s going to be okay

If you haven’t been screened yet, this video is a reminder that your concerns are valid and should be acknowledged when talking with your doctor.

Q&A: How can people approach their healthcare providers about colon cancer screening?

Preparing for your appointment

You don’t need to have all the answers – your doctor will be there to provide clarity and guide you.

  • Note your personal and family history: Know if any close relatives had colon cancer or polyps.
  • Check for symptoms: Note any changes in bowel habits, persistent pain, or blood.
  • Have your questions ready: Use our downloadable discussion guide to stay organized and keep the conversation flowing throughout your visit.

Simple questions to ask your doctor

Not sure what to say? Use this checklist to lead the way:

  • Your status, risk, and options
    • At my age, am I due for a colon cancer screening?
    • Based on my family history, am I at a higher risk?
    • What screening methods are available to me?
    • Which test do you think is right for my lifestyle, and why?
    • Can I use a noninvasive, use-at-home test like Cologuard Plus?*
  • The logistics
    • Do I need to adjust my current medications or diet?
    • Do I need to take time off from work?
  • The potential costs
    • Will my insurance cover this as a preventive screening?
    • Do I need to pay for a follow-up colonoscopy after a positive 
use-at-home test?
  • Your results
    • When and how will I receive my test results?
    • What happens next if my test comes back positive or negative?

What if you don’t have a doctor?

No problem at all. If you’re 45 and at average risk for colon cancer, you can request a Cologuard Plus test through telehealth. This lets you consult with a health provider by phone and screen from the privacy of your home without visiting a doctor’s office.


Request via telehealth

Understanding your screening options 

Here are two paths for average-risk adults:

  • Visual exams: Like a colonoscopy, which looks inside the colon.
  • Stool-based tests: Like Cologuard Plus, which is a noninvasive, use-at-home collection kit for average-risk adults 45+.

Both methods can detect colon cancer, but they are not identical. Your conversation with your doctor is the best time to review these options and choose the one that fits your needs and lifestyle.

Why this conversation matters

While it may feel a little awkward at first, remember that your doctor is your partner in this journey and has heard these questions many times before.

By starting this conversation, you’re taking a powerful step toward staying present for the moments and people who matter most to you. Whether you choose a noninvasive stool-based test or a visual exam such as a colonoscopy, the most important thing is to get screened. You don't have to navigate this alone — be honest, advocate for your health, and give yourself the peace of mind you deserve.

Safe.
Noninvasive.
FDA-approved.