Cologuard® is a
one-of-a-kind, non-invasive colon cancer screening test

The Cologuard difference

There are other non-invasive screening tests for colon cancer, like FIT*, but none of them are like Cologuard.

Cologuard is the first and only test that looks for both abnormal DNA and blood in stool.
Plus, Cologuard's Customer Care Center supports you the entire way.

How does Cologuard one-up other non-invasive screening tests?

Watch the video now and see how easy Cologuard can be to use

GET MORE WITH COLOGUARD

How does Cologuard compare to FIT?

More cancers found. More time between screenings.

Cologuard FIT

92%

of colon cancers found1

74%

of colon cancers found1

 42%

of precancers detected1

24%

of precancers detected1 

Blood & Abnormal DNA

detected in stool 

Only Blood

detected in stool

 3 years

until next screening2

1 year

until next screening 

Cologuard performance is based on a large clinical study of more than 10,000 patients ages 50-84, Cologuard found more cancers and precancers than an ordinary blood stool test (e.g. FIT). False positive results can occur and should be discussed with your doctor and followed by a colonoscopy.1,2

*FIT (fecal immunochemical test)

OC-FIT CHEK, Polymedco, Inc.

How does Cologuard work?

The science behind Cologuard

Learn what makes Cologuard powerful at finding colon cancer.

Watch the video now and see how easy Cologuard can be to use

Gather cells

Every day your colon sheds cells that are collected when stool passes through.

Look at DNA

Cologuard examines the DNA of collected cells.

Detect cancerous signs

If Cologuard detects abnormal DNA or blood, this may indicate precancer or cancer.

Don't just take it from us.

Hear from real people who have screened using Cologuard.

Read our Patient Stories
Scott, 51, is a colorectal cancer survivor who was screened with Cologuard.

You have questions. We have answers.

  • Who is Cologuard for?

    Cologuard is for people 45 years of age and older who are at average risk for colon cancer. Cologuard is not a replacement for colonoscopy in high risk individuals.

    More about who Cologuard is for

  • How effective is Cologuard?

    Cologuard is shown to be effective. In a clinical study of 10,000 participants ages 50-84 years old, of average risk for colorectal cancer, Cologuard found 92% of cancer.1
    More about how Cologuard is effective 

    1. Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-1297.

  • Is Cologuard a FIT* test?

    No, Cologuard is the only non-invasive colorectal screening test that uses advanced stool DNA technology to detect the DNA and hemoglobin (red blood cells) released from abnormal cells, if present. Rx only

  • Can Cologuard detect polyps?

    Yes, Cologuard can detect some precancerous polyps that grow on the wall of the colon and may develop into cancer.1
    More about how Cologuard is effective 

    1. Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-1297.

  • How will I know if my stool sample is ‘normal’?

    It’s important to get a sample that is typical for you in terms of consistency (loose stools are okay if that’s normal for you). However, if you are sick and have diarrhea, you should wait until you feel better to collect a sample. If you have specific questions, call Customer Care at 1-844-870-8870. For instructions on how to provide your sample, watch the How to Use video and read more here.

References
1. Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-1297.
2. Wolf AMD, Fontham ETH, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guidelines update from the American Cancer Society. CA Cancer J Clin. 2018;68(4):250-281.

Request Cologuard online.
No appointment needed.