Why start
at age 45?

Medical guidelines recommend screening for colon cancer starting at age 45, instead of waiting until 501

For years, the recommendation was for adults at average risk for colon cancer to start screening at age 50, but the American Cancer Society's guidelines have changed: now adults at average risk should start screening at age 45.1,2

Additional reasons to screen early

Colon cancer is increasing in younger adults2
In a study of people diagnosed with colorectal cancer, 1 in 7 was under the age of 503

How Cologuard® can help

Cologuard finds 92% of colon cancers, even in early stages (including 94% of Stage I and Stage II colon cancers)5,6*†
Cologuard performed better than another leading noninvasive test at finding colon cancer6

* Cologuard sensitivity, per stage of cancer: I: 90% (n=29); II: 100% (n=21); III: 90% (n=10); IV: 75% (n=4)6

Cologuard performance in adults ages 45-49 is estimated based on a large clinical study of patients 50 and older. False positives and false negatives may occur. In this clinical study, 13% of people without cancer received a positive result (false positive) and 8% of people with cancer received a negative result (false negative)5,6


1. American Cancer Society. When should you start getting screened for colorectal cancer? Published February 4, 2021. Accessed February 11, 2021. https://www.cancer.org/latest-news/american-cancer-society-updates-colorectal-cancer-screening-guideline.html 2. Wolf AMD, Fontham ETH, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA Cancer J Clin. 2018;68(4):250-281. 3. Abdelsattar ZM, Wong SL, Regenbogen SE, Jomaa DM, Hardiman KM, Hendren S. Cancer. 2016;122(6):929-34. 4. National Cancer Institute. SEER cancer stat facts: colorectal cancer. Accessed February 11, 2021. https://seer.cancer.gov/statfacts/html/colorect.html 5. Ahlquist DA. Multi-target stool DNA test: a new high bar for noninvasive screening. Dig Dis Sci. 2015;60(3):623-633. 6. Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-1297.


Cologuard is effective and easy to use at home

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from a healthcare provider

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